PANDER Induced Cell-Death Networks in Pancreatic Islets - Study GBCO2301
Genomics Study Specifications
| Study Name | PANDER Induced Cell-Death Networks in Pancreatic Islets | ||
|---|---|---|---|
| Contact Name | Bryan A. Wolf (Childrens Hospital of Philadelphia) | ||
| Publication | http://www.ncbi.nlm.nih.gov/pubmed/16412588 | ||
| My Strategies | Return to My Strategies page | ||
| Classification | Cell stimulation/injury; Islet/beta-cell stimulation/injury | ||
| Links | |||
| BCBC Release Date | February 06, 2006 | ||
| Public Release Date | February 06, 2006 | ||
| Citation | Burkhardt BR, Greene SR, White P, Wong RK, Brestelli JE, Yang J, Robert CE, Brusko TM, Wasserfall CH, Wu J, Atkinson MA, Gao Z, Kaestner KH, Wolf BA. PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21). Gene. 2006. 369:134-41 | ||
| Synopsis |
Expression profiling using the mouse PancChip version 5.0 was used to elucidate the genetic mechanisms of PANDER-induced cell death in Pancreatic Islets. Murine islets were treated with PANDER for 48 or 72 h (n=4 and n=3 respectively). Following linear amplification, the RNA was matched for purity using Quantitative PCR.
No goal information provided
No approach information provided
No result information provided
No conclusion information provided
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| Platform types | Expression microarray, Expression | ||
| Platforms |
Show platform Mouse PancChip
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| Study Design Type |
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| Study Factors | Show study factors | ||
| Study Assays | Show study assays | ||
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Repositories
| Kaestner Lab | |
|---|---|
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Stock #: Not provided Availability Notes: Not provided |
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