ROSA26-LSL-mtGCK - Mouse Strain RES842
Mouse Information
| Common Name: | ROSA26-LSL-mtGCK |
|---|---|
| MGI Official Name: | Gt(ROSA)26Sortm1(GCK*)Ydor |
| Description: | Glucokinase containing the Y214C activating mutation, causing severe persistent hyperinsulinemic hypoglycemia (Diabetes 53:2164-2168, 2004) was targeted to the ROSA26 locus, preceded by a lox-stop-lox sequence and followed by IRES-EGFP.
|
| Categories: |
Cre-lox inducible |
Genetic Alterations
| 1) BAC or Transgene Insertion | |
|---|---|
| Type of Vector | Plasmid |
| Promoter |
ROSA26
(ROSA26 - MGI:14910)
|
| Expressed Gene | Glucokinase (GCK - MGI:24385) |
| Description of Transgene | ROSA26 - lox-stop-lox- mutant GCK (Y214C) - IRES-EGFP |
| Vector Genbank File | pRosa26Gckmt.gb |
| Citations | Not provided |
Strain Information
| Strain Type: | Mixed |
|---|---|
| Chimera/Founder Genetic Background: | 129X1/SvJ |
| Current Genetic Background: | 129P2/OlaHsd (date recorded: Not provided) |
| Strain Description: | 129, now few genetations crossed into CD1. |
Associated Images
| Image 1 | |
|---|---|
|
Description: Not provided Reference: Not provided |
Repositories
| Dor Lab | |
|---|---|
 Request this resource
|
Stock #: VUMC-JZ Availability Notes: Not provided |
Contact Information
| Preferred Contact | |
|---|---|
| Name | Yuval Dor |
| Institution | Hebrew University-Hadassah Medical School, Ein Kerem |
| Phone | 972-2-6757181 |
| yuvald@ekmd.huji.ac.il | |
| Primary Lab Contact | |
| Name | Yuval Dor |
| Institution | Hebrew University-Hadassah Medical School, Ein Kerem |
| Phone | 972-2-6757181 |
| yuvald@ekmd.huji.ac.il | |
Associated Publications
No publications associated
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