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Polyclonal Rat IAPP raised in Rabbit - Antibody RES266


Antibody Information

Antibody ID: AB1041
Antigen: IAPP (NCBI Gene ID: 24476)
Type: Polyclonal
Isotype: Not Applicable
Immunogen Source: Peptide
Raised In: Rabbit
Peptide: IAPP(aa11-aa37)
Source of Antigen: Rat
Cross Reacts With: Mouse,Rat,Human
Affinity Purified: Serum
Purity Details: Not provided
Positive Control: Adult Rat or mouse pancreas
Notes: Not provided

Applications and Uses

Application Concentration Storage Buffer Protocols and Description
IHC 1:2000 TSA PBS with azide Description: Using TSA amplification
Protocols:
  1. Fluorescence
IHC 1:1000 PBS with azide Description: Not provided
Protocols:
    Not provided
IHC-P 1:1000 PBS with azide Description: Using TSA amplification
Protocols:
  1. Peroxidase

Associated Images

Image 1
Description:

In wild-type embryos, only 8% (19 cells out of 244 cells) of the IAPP-expressing cells do not express insulin (I), whereas in pPDX1-Notch1ICD embryos, approximately 50% (29 cells out of 63 cells) of IAPP-positive cells do not express insulin (J)



Reference:

Hald et al: Dev Biol 2003


Repositories

BCBC Antibody Core
Request this resource Stock #: Rab771
Availability Notes: Sent in 25ul amounts

Contact Information

Preferred Contact
Name Signe Ingvarsen
Institution Novo Nordisk A/S
Phone +45 30750390
Email sgi@novonordisk.com

Associated Publications

Publication Citation
12921743 Hald J, Hjorth JP, German MS, Madsen OD, Serup P, Jensen J Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development. (2003) Dev Biol 260: 426-37 (Added May 15, 2013)
1850107 Madsen OD, Nielsen JH, Michelsen B, Westermark P, Betsholtz C, Nishi M, Steiner DF Islet amyloid polypeptide and insulin expression are controlled differently in primary and transformed islet cells. (1991) Mol Endocrinol 5: 143-8 (Added August 18, 2010)

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Resource Tags

AbCore, antibody, IAPP, Polyclonal, Rat

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Resource History & Actions

Approved on
Last modified on May 07, 2013
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