Ptf1aflox - Mouse Strain RES248
Mouse Information
| Common Name: | Ptf1aflox |
|---|---|
| MGI Official Name: | Ptf1atm3Cvw |
| Description: | Conditional null allele of Ptf1a. LoxP sites flanking exon 1 and 2 (entire coding region of Ptf1a). |
| Categories: |
Cre-lox floxed alleles |
Genetic Alterations
| 1) Targeted Mutagenesis | |
|---|---|
| Type of Allele | Conditional Null |
| Targeted Gene | Pancreas Specific Transcription Factor, 1a (Ptf1a - NCBI GeneID:19213) |
| Targeted Allele |
Targeted Mutation 3
(Ptf1atm3Cvw - MGI:1328312)
|
| Description of Targeting Vector | 5' loxP site was placed 1.6 kb upstream of the transcription start site. The FRT-Neo-FRT cassette was placed 100 bp after the transcription stop site followed by the 3' loxP. Upon Germline transmission, the neomycin cassette will be deleted by a FLPe deleter mouse. This will result in the final Ptf1a floxed allele. |
| Targeting Vector Genbank File |
Targeting_Vector.gb |
| Citations | Not Available |
Strain Information
| Strain Type: | Not provided |
|---|---|
| Chimera/Founder Genetic Background: | Not provided |
| Current Genetic Background: | Not provided (date recorded: Not provided) |
| Strain Description: | Not provided |
Associated Images
| No associated images have been supplied | |
Repositories
| Wright Lab | |
|---|---|
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|
Stock #: Not provided Availability Notes: Not provided |
Contact Information
| Preferred Contact | |
|---|---|
| Name | Chris Wright |
| Institution | Vanderbilt University |
| Phone | 615-343-8256 |
| chris.wright@vanderbilt.edu | |
| Primary Lab Contact | |
| Name | Not provided |
| Institution | Not provided |
| Phone | Not provided |
| Not provided | |
Associated Publications
No publications associated
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