Mouse Information
| Common Name: |
Insulin-CreER |
| MGI Official Name: |
Tg(RIP-Cre/ESR1)Ydor |
| Description: |
A transgenic mouse expression tamoxifen-inducible Cre recombinase under rat insulin promoter. Upon the injection of tamoxifen, loxP-flanked DNA sequences in beta cells will be deleted. |
| Categories: |
Cre-lox inducible
|
Genetic Alterations
| 1) BAC or Transgene Insertion |
|---|
| Type of Vector |
Plasmid
|
| Promoter |
Insulin
(Ins - MGI:16333)
|
| Expressed Gene |
Tamoxifen-inducible Cre recombinase
(CreER)
|
| Description of Transgene |
The RIPCreER construct was generated by fusing a 0.66-kilobase SmaI HindIII fragment of the RIP2 promoter to aminimal hsp68 promoter, and placing the chimaeric promoter upstream of CreER.
|
| Vector Genbank File |
Not provided |
| Citations |
| PubMedID |
Citation |
| 15129273 |
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. (2004) Nature 429: 41-6
(Added 2005-08-16 09:28:01) |
|
Strain Information
| Strain Type: |
Mixed |
| Chimera/Founder Genetic Background: |
FVB/N |
| Current Genetic Background: |
ICR (date recorded: Not provided)
|
| Strain Description: |
Not provided |
Associated Images
|
No associated images have been supplied
|
Repositories
Contact Information
| Preferred Contact |
| Name |
Yuval Dor |
| Institution |
Hebrew University-Hadassah Medical School, Ein Kerem |
| Phone |
972-2-6757181 |
| Email |
yuvald@ekmd.huji.ac.il |
| Primary Lab Contact |
| Name |
Yuval Dor |
| Institution |
Hebrew University-Hadassah Medical School, Ein Kerem |
| Phone |
972-2-6757181 |
| Email |
yuvald@ekmd.huji.ac.il |
Associated Publications
No publications associated
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