Nkx6.1DsRed2/+ - Mouse Strain RES205
Mouse Information
| Common Name: | Nkx6.1DsRed2/+ |
|---|---|
| MGI Official Name: | B6-Nkx6-1tm1Msan |
| Description: | An IRES-DsRed2 cassette was introduced into exon 1 of the Nkx6.1 genomic sequence. The insertion generates a null allele. DsRed2 expression is not detected in these mice. |
| Categories: | None specified. |
Genetic Alterations
| 1) Targeted Mutagenesis | |
|---|---|
| Type of Allele | Global Null |
| Targeted Gene | Nkx6.1 (Nkx6-1 - NCBI GeneID:18096) |
| Targeted Allele |
targeted mutation
(Nkx6.1tm1(DsRed2))
|
| Description of Targeting Vector | Through homologous recombination in ES cells an IRES-DsRed2-pA-loxP-pA-puro-SV40prom-loxP cassette was inserted via PmeI and ClaI into a modified KpnI site within exon 1. The KpnI site is located 3' of the translation start site of Nkx6.1. |
| Targeting Vector Genbank File |
Nkx6.1_DsRed2sequence.doc |
| Citations | Not Available |
Strain Information
| Strain Type: | Inbred Strain |
|---|---|
| Chimera/Founder Genetic Background: | 129S6/SvEvTac |
| Current Genetic Background: | C57BL/6J (date recorded: Not provided) |
| Strain Description: | Not provided |
Associated Images
| No associated images have been supplied | |
Repositories
| Sander Lab | |
|---|---|
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|
Stock #: Not provided Availability Notes: Not provided |
Contact Information
| Preferred Contact | |
|---|---|
| Name | Maike Sander |
| Institution | University of California at San Diego |
| Phone | 858-246-0843 |
| masander@ucsd.edu | |
| Primary Lab Contact | |
| Name | Not provided |
| Institution | Not provided |
| Phone | Not provided |
| Not provided | |
Associated Publications
No publications associated
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