Mouse skeletal muscle - controls, streptozotocin diabetes and insulin treated - Study GBCO2335
Genomics Study Specifications
| Study Name | Mouse skeletal muscle - controls, streptozotocin diabetes and insulin treated | ||
|---|---|---|---|
| Contact Name | Ronald C Kahn (Joslin Diabetes Center and Harvard Medical School) | ||
| Publication | http://www.ncbi.nlm.nih.gov/pubmed/12149437 | ||
| My Strategies | Return to My Strategies page | ||
| Classification | Cell stimulation/injury | ||
| Links | |||
| BCBC Release Date | April 13, 2009 | ||
| Public Release Date | April 13, 2009 | ||
| Citation | Yechoor VK, Patti ME, Saccone R, Kahn CR. Coordinated patterns of gene expression for substrate and energy metabolism in skeletal muscle of diabetic mice. Proc Natl Acad Sci U S A. 2002. 99:10587-92 | ||
| Synopsis |
Metabolic abnormalities underlying diabetes are primarily the result of the lack of adequate insulin action and the associated changes in protein phosphorylation and gene expression. Affymetrix oligonucleotide microarrays were used to study the changes in the transcriptional program of mouse skeletal muscle in insulin-deficient diabetes. Mice which were made diabetic by streptozotocin treatment were compared to controls. Also, the reversibility of these changes was ascertained by treating a subset of the diabetic mice with insulin.
No goal information provided
No approach information provided
No result information provided
No conclusion information provided
No studies listed
|
||
| Platform types | Expression microarray, Expression | ||
| Platforms |
Show platform Affymetrix MG_U74A
|
||
| Study Design Type |
|
||
| Study Factors | Show study factors | ||
| Study Assays | Show study assays | ||
Biomaterials Graph
ArrayExpress
Access to Study Data
This Study Data is publicly available to all users.
Gene List(s)
Loading...
Repositories
| Stoeckert Lab | |
|---|---|
 Request this resource
|
Stock #: Not provided Availability Notes: Not provided |
Comments
There are no comments for this entry.
Login to add comments
Access Status
This resource is publicly viewable.
Request this Resource
Resource Tags
Resource History & Actions
Related resources
Loading...
