Mouse Information
| Common Name: |
Nkx2.2 null |
| MGI Official Name: |
Nkx2-2tm5(null)Suss |
| Description: |
These mice contain a deletion of the Nkx2.2 coding region to create a null allele. |
| Categories: |
None specified.
|
Genetic Alterations
| 1) Targeted Mutagenesis |
|---|
| Type of Allele |
Global Null
|
| Targeted Gene |
Nkx2.2
(Nkx2.2 - NCBI GeneID:18088)
|
| Targeted Allele |
Null
(Nkx2.2tm5(null) - MGI:97347)
|
| Description of Targeting Vector |
14kb genomic DNA containing PGK:neo in place of exon1 and exon2 of Nkx2.2.
|
| Targeting Vector Genbank File |
Not provided
|
| Citations |
| PubMedID |
Citation |
| 9584121 |
Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due (1998) Development 125: 2213-21
(Added 2005-04-13 12:53:51) |
|
Strain Information
| Strain Type: |
Outbred |
| Chimera/Founder Genetic Background: |
129X1/SvJ |
| Current Genetic Background: |
Swiss Black (date recorded: Not provided)
|
| Strain Description: |
Not provided |
Associated Images
|
No associated images have been supplied
|
Repositories
Contact Information
| Preferred Contact |
| Name |
Lori Sussel |
| Institution |
Columbia University |
| Phone |
212-851-5115 |
| Email |
lgs2@columbia.edu |
| Primary Lab Contact |
| Name |
Lori Sussel |
| Institution |
Columbia University |
| Phone |
212-851-5115 |
| Email |
lgs2@columbia.edu |
Associated Publications
No publications associated
Comments
There are no comments for this entry.
Login to add comments
Request this resource
This resource is publicly viewable.
