TRAFEX - TRAnscription Factor EXpression survey
TRAFEX is a searchable database of gene expression data. To begin using TRAFEX, scroll down to the the three search options: Predefined Search, Simple Search, and Complex Search. All settings are saved as you navigate from one search option to another.
A global survey of RNA from 14 fetal and 12 adult human organs by RT-PCR determined the expression patterns of 790 genes encoding DNA-binding transcription factors. The data can be searched and sorted to identify sets of transcription factors with expression restricted to a given organ or to particular organ groups. These data are a resource to help define the spectrum of transcription factor control, contribute to the elucidation of transcription factor cascades responsible for the development and maintenance of each organ, and provide a baseline to study the effects of disease or developmental defects.
Contributed by Dr. Ray MacDonald, as published: Kong YM, MacDonald RJ, Wen X, Yang P, Barbera VM, Swift GH. A comprehensive survey of DNA-binding transcription factor gene expression in human fetal and adult organs. Gene Expr Patterns, 2006 PubMed
Additional analysis is available at genomics.betacell.org
Retrieve list of genes expressed in fetal pancreas that have an expression level
≥2, ≥3, ≥4,
Retrieve list of genes expressed in adult pancreas and islets that have an expression level
≥2, ≥3, ≥4
Retrieve list of genes that are differentially expressed in the pancreas that have a differential value of
-4, -3, -2, -1, 0, 1, 2, 3, 4