TRAFEX - TRAnscription Factor EXpression survey
A description, tutorial and FAQ will soon be available.
Click here for a sample search for PTF1A, IPF1, NeuroD1 and Neurog3
TRAFEX is a searchable database of gene expression data. To begin using TRAFEX, scroll down to the the three search options: Predefined Search, Simple Search, and Complex Search. All settings are saved as you navigate from one search option to another.
A global survey of RNA from 14 fetal and 12 adult human organs by RT-PCR determined the expression patterns of 790 genes encoding DNA-binding transcription factors. The data can be searched and sorted to identify sets of transcription factors with expression restricted to a given organ or to particular organ groups. These data are a resource to help define the spectrum of transcription factor control, contribute to the elucidation of transcription factor cascades responsible for the development and maintenance of each organ, and provide a baseline to study the effects of disease or developmental defects.
Contributed by Dr. Ray MacDonald,
as published: Kong YM, MacDonald RJ, Wen X, Yang P, Barbera VM, Swift GH.
A comprehensive survey of DNA-binding transcription factor gene expression
in human fetal and adult organs. Gene Expr Patterns, 2006
PubMed
Additional analysis is available at genomics.betacell.org
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Retrieve list of genes expressed in fetal pancreas that have an expression level
≥2, ≥3, ≥4, -
Retrieve list of genes expressed in adult pancreas and islets that have an expression level
≥2, ≥3, ≥4 -
Retrieve list of genes that are differentially expressed in the pancreas that have a differential value of
-4, -3, -2, -1, 0, 1, 2, 3, 4
| Symbol | TF Family | Stage | CNT 34 | CNT 234 | |||||||||||||
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ABLIM1
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LIM | ADULT | 13 | 13 | 3 | 4 | 4 | 3 | 3 | 3 | 3 | 4 | 3 | 4 | 3 | 3 | 4 |
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ABLIM3
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LIM | ADULT | 11 | 13 | 2 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 2 | 3 | 3 | 3 | 3 |
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ADNP
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HD | ADULT | 13 | 13 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 |
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AGGF1
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FH | ADULT | 6 | 12 | 1 | 2 | 3 | 2 | 3 | 3 | 2 | 2 | 3 | 2 | 3 | 3 | 2 |
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AHR
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HLH | ADULT | 7 | 12 | 3 | 1 | 3 | 2 | 2 | 2 | 3 | 3 | 3 | 2 | 3 | 3 | 2 |
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AIRE
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RING | ADULT | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 3 |
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APBB1
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STAT | ADULT | 10 | 10 | 3 | 4 | 4 | 3 | 3 | 3 | 0 | 4 | 0 | 4 | 3 | 1 | 4 |
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AR
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NR | ADULT | 5 | 11 | 2 | 1 | 4 | 2 | 0 | 3 | 4 | 2 | 2 | 3 | 3 | 2 | 2 |
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ARID1A
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MISC | ADULT | 1 | 1 | 4 | ||||||||||||
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ARID5A
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MISC | ADULT | 11 | 13 | 3 | 3 | 3 | 3 | 3 | 2 | 3 | 3 | 2 | 3 | 3 | 3 | 3 |
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ARNT
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HLH | ADULT | 12 | 13 | 3 | 3 | 3 | 3 | 2 | 3 | 3 | 3 | 3 | 3 | 4 | 3 | 3 |
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ARNTL
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HLH | ADULT | 13 | 13 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 |
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ASCL1
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HLH | ADULT | 2 | 2 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4 |
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ASCL3
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HLH | ADULT | 1 | 2 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 3 | 2 |
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ASH1L
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MISC | ADULT | 10 | 13 | 2 | 3 | 3 | 2 | 3 | 3 | 2 | 3 | 3 | 3 | 3 | 3 | 3 |
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ATBF1
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HD | ADULT | 1 | 8 | 2 | 1 | 2 | 2 | 0 | 1 | 2 | 3 | 0 | 2 | 2 | 2 | 1 |
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ATF1
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BZIP | ADULT | 9 | 13 | 2 | 2 | 3 | 2 | 3 | 3 | 2 | 3 | 3 | 3 | 3 | 3 | 3 |
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ATF2
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BZIP | ADULT | 9 | 10 | 1 | 3 | 2 | 1 | 3 | 3 | 1 | 3 | 3 | 3 | 3 | 3 | 3 |
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ATF3
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BZIP | ADULT | 10 | 13 | 3 | 2 | 3 | 2 | 3 | 3 | 2 | 4 | 3 | 3 | 4 | 3 | 3 |
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ATF5
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BZIP | ADULT | 11 | 13 | 3 | 2 | 3 | 3 | 3 | 3 | 4 | 3 | 3 | 3 | 3 | 3 | 2 |
