Cooperative Agreement Funding Mechanism
The NIDDK, through the BCBC Cooperative Agreement funding mechanisms, supports a wide range of research projects focused on understanding the underlying mechanisms of beta cell development, stem cell biology, and beta cell regeneration, with the overarching goal of developing cellular therapies for Type 1 diabetes.
The RFA page for current funding cycle is available.
Project Descriptions (17 Grants)
Lead grant investigators are flagged with a yellow star,
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Architecture and communication controlling the efficient generation of beta cells
Beta Cell Regeneration by Reprogramming of Adult Pancreatic Cells
Project Investigator:
Coordinating Center for Beta Cell Biology Consortium
Epigenetic and Genetic Control of Human and Murine Beta Cell Development and Fate
Epigenetic strategies for the in vitro generation of replacement beta cells
Epigenomics of the regenerating and aging beta-cell
Epitenetic regulation and enhancement of beta cell differentiation
Project Investigator:
Expanding beta-cell mass
Formation of endocrine pancreas progenitors
Generation of functional beta cells from stem and progenitor cells
Genetic control of pancreatic endocrine cell development
Molecular Mechanisms of Human and Murine Beta Cell Proliferation and Regeneration
Project Investigators:
Multi-Disciplinary Approaches to Driving Therapeutic Human Beta Cell Replication
Novel Sources of Transplantable Beta-cell Replacements
Signaling and Epigenetic Control of Beta Cell Development and Regeneration
Project Investigators:

Chris Wright
Anne Grapin-Botton
Ray MacDonald
Mark Magnuson
Henrik Semb
Pedro Herrera
Ole Madsen
Christian Stoeckert
Yi Zhang
Seung Kim
Anil Bhushan
Howard Chang
Michael Snyder
Maike Sander
Jorge Ferrer
Klaus Kaestner
Karl Willert
Doris Stoffers
Arthur Riggs
Mike German
Matthias Hebrok
Feroz Papa
Didier Stainier
Maureen Gannon
Gordon Keller
Philip Streeter
Mervin Yoder
Peter Zandstra
Guoqiang Gu
Lori Sussel
Alvin Powers
Dale Greiner
David Harlan
Leonard Shultz
Roland Stein
Andrew Stewart
Chris Newgard
Markus Grompe
Mark Kay
Doug Melton
Qiao Zhou
Kenneth Zaret
Gerard Gradwohl
Harry Heimberg
Eugene Kolker
Raphael Scharfmann