. . Login · Contact · Version 3.9

Cooperative Agreement Funding Mechanism

The NIDDK, through the BCBC Cooperative Agreement funding mechanisms, supports a wide range of research projects focused on understanding the underlying mechanisms of beta cell development, stem cell biology, and beta cell regeneration, with the overarching goal of developing cellular therapies for Type 1 diabetes.

The RFA page for current funding cycle is available.



Project Descriptions (17 Grants)

Lead grant investigators are flagged with a yellow star, Team Leader.

Architecture and communication controlling the efficient generation of beta cells



Beta Cell Regeneration by Reprogramming of Adult Pancreatic Cells

Project Investigator:



Coordinating Center for Beta Cell Biology Consortium



Epigenetic and chemical approaches to generate function beta cells

Project Investigator:



Epigenetic and Genetic Control of Human and Murine Beta Cell Development and Fate



Epigenetic strategies for the in vitro generation of replacement beta cells



Epigenomics of the regenerating and aging beta-cell

Project Investigators:



Epitenetic regulation and enhancement of beta cell differentiation

Project Investigator:



Expanding beta-cell mass



Formation of endocrine pancreas progenitors



Generation of functional beta cells from stem and progenitor cells



Genetic control of pancreatic endocrine cell development



Molecular Mechanisms of Human and Murine Beta Cell Proliferation and Regeneration



Multi-Disciplinary Approaches to Driving Therapeutic Human Beta Cell Replication

Project Investigators:



Novel Sources of Transplantable Beta-cell Replacements



Regenerating Beta Cells by Lineage Reprogramming

Project Investigators:



Signaling and Epigenetic Control of Beta Cell Development and Regeneration