Collaborative Bridging Project Program
The Collaborative Briding Project (CBP) program is a funding mechanism designed to encourage synergy via collaboration amongst BCBC investigators, as well as with scientists outside the BCBC. It is expected that these collaborative efforts will generate new reagents and resources or apply cutting-edge technology that has the potential to accelerate research relevant to the BCBC.
2009-2010 Collaborative Bridging Projects
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2008-2009 Collaborative Bridging Projects
SPEED - Secreted Proteins from Endothelial cells for Endocrine Development
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· Investigators: Harry Heimberg, Gerard Gradwohl, Eugene Kolker, Kenneth Zaret, Gordon Keller, Ondine Cleaver
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· Investigators: Harry Heimberg, Gerard Gradwohl, Eugene Kolker, Kenneth Zaret, Gordon Keller, Ondine Cleaver
HUMANE2 - HUmanized Mice for Assays to Normalize Endocrine Pancreas Function
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· Investigators: Pedro Herrera, Alvin Powers, Leonard Shultz, Dale Greiner
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· Investigators: Pedro Herrera, Alvin Powers, Leonard Shultz, Dale Greiner
EXHUM - Chromatin marks and mRNA expression in human pancreatic cell populations
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· Investigators: Chris Stoeckert, Klaus Kaestner, Markus Grompe
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· Investigators: Chris Stoeckert, Klaus Kaestner, Markus Grompe
BETA3 - Isolation and expansion of hESC-derived pancreatic cell populations
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· Investigators: Mark Magnuson, Chris Wright, Gordon Keller, Peter Zandstra
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· Investigators: Mark Magnuson, Chris Wright, Gordon Keller, Peter Zandstra
FATE - Functional Analysis of TM4SF4 during Embryogenesis
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· Investigators: Lori Sussel, Didier Stainier, Kristin Artinger
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· Investigators: Lori Sussel, Didier Stainier, Kristin Artinger
SASsy3 - Signal Activated Sentinels for beta-cell development and regeneration
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· Investigators: Mark Magnuson, Palle Serup, Ray MacDonald, Kenneth Zaret, Anne Grapin-Botton
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· Investigators: Mark Magnuson, Palle Serup, Ray MacDonald, Kenneth Zaret, Anne Grapin-Botton
preBETA ID - Reagents for beta cell precursor identification
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· Investigators: Philip Streeter, Gordon Keller
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· Investigators: Philip Streeter, Gordon Keller
2007-2008 Collaborative Bridging Projects
SASsy - Signal Activated Sentinels for beta-cell development and regeneration
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· Investigators: Palle Serup, Ray MacDonald, Kenneth Zaret, Anne Grapin-Botton
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· Investigators: Palle Serup, Ray MacDonald, Kenneth Zaret, Anne Grapin-Botton
DDMESC - Development of methods and reagents for directed differentiation of mouse embryonic stem cells toward pancreatic beta cells through chemical screening
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· Investigator: Doug Melton
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· Investigator: Doug Melton
BRAVE - Beta cell Regeneration And Vascular Endothelium
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· Investigators: Harry Heimberg, Yuval Dor, Pedro Herrera, Eli Keshet
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· Investigators: Harry Heimberg, Yuval Dor, Pedro Herrera, Eli Keshet
HUMANE - HUmanized Mice for Assays to Normalize Endocrine pancreas function
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· Investigators: Pedro Herrera, Leonard Shultz, Dale Greiner
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· Investigators: Pedro Herrera, Leonard Shultz, Dale Greiner
MAD BETA - Monoclonal Antibodies Directed toward the Developing Beta Cell
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· Investigators: Ole Madsen, Gerard Gradwohl, Joshua LaBaer, Kenneth Zaret, Raphael Scharfmann, Philip Streeter, Gordon Keller
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· Investigators: Ole Madsen, Gerard Gradwohl, Joshua LaBaer, Kenneth Zaret, Raphael Scharfmann, Philip Streeter, Gordon Keller
BETA2 - Pancreatic Beta Cells from Human ES Cells 2
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· Investigators: Mark Magnuson, Gordon Keller, Peter Zandstra
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· Investigators: Mark Magnuson, Gordon Keller, Peter Zandstra
2006-2007 Collaborative Bridging Projects
HUMANE - HUmanized Mice for Assays to Normalize Endocrine pancreas function
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· Investigators: Pedro Herrera, Leonard Shultz, Dale Greiner
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· Investigators: Pedro Herrera, Leonard Shultz, Dale Greiner
DDMESC - Development of methods and reagents for directed differentiation of mouse embryonic stem cells toward pancreatic beta cells through chemical screening
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· Investigator: Doug Melton
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· Investigator: Doug Melton
BETA - Pancreatic Beta Cells from Human ES Cells
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· Investigators: Mark Magnuson, Chris Wright, Gordon Keller
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· Investigators: Mark Magnuson, Chris Wright, Gordon Keller
MAD BETA - Monoclonal Antibodies Directed toward the Developing Beta Cell
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· Investigators: Jan Jensen, Ole Madsen, Gerard Gradwohl, Joshua LaBaer, Philip Streeter, Gordon Keller
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· Investigators: Jan Jensen, Ole Madsen, Gerard Gradwohl, Joshua LaBaer, Philip Streeter, Gordon Keller
SASsy - Signal Activated Sentinels for beta-cell development and regeneration
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· Investigators: Palle Serup, Ray MacDonald, Kenneth Zaret, Anne Grapin-Botton
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· Investigators: Palle Serup, Ray MacDonald, Kenneth Zaret, Anne Grapin-Botton
BRAVE - Beta cell Regeneration And Vascular Endothelium
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· Investigators: Harry Heimberg, Yuval Dor, Pedro Herrera, Eli Keshet
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· Investigators: Harry Heimberg, Yuval Dor, Pedro Herrera, Eli Keshet
MATURE - Transcriptional networks of the mature beta cell
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· Investigators: Roland Stein, Lori Sussel, Klaus Kaestner, Chris Newgard
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· Investigators: Roland Stein, Lori Sussel, Klaus Kaestner, Chris Newgard
NEAT - NEtwork Analysis of Transcription in the developing pancreas
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· Investigators: Lori Sussel, Klaus Kaestner, Maike Sander, Shridhar Hannenhalli
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· Investigators: Lori Sussel, Klaus Kaestner, Maike Sander, Shridhar Hannenhalli
