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Collaborative Bridging Project Program

The Collaborative Briding Project (CBP) program is a funding mechanism designed to encourage synergy via collaboration amongst BCBC investigators, as well as with scientists outside the BCBC. It is expected that these collaborative efforts will generate new reagents and resources or apply cutting-edge technology that has the potential to accelerate research relevant to the BCBC.

2009-2010 Collaborative Bridging Projects

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2008-2009 Collaborative Bridging Projects

CBP
SPEED - Secreted Proteins from Endothelial cells for Endocrine Development
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· Investigators: Harry Heimberg, Gerard Gradwohl, Eugene Kolker, Kenneth Zaret, Gordon Keller, Ondine Cleaver

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CBP
HUMANE2 - HUmanized Mice for Assays to Normalize Endocrine Pancreas Function
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· Investigators: Pedro Herrera, Alvin Powers, Leonard Shultz, Dale Greiner

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CBP
EXHUM - Chromatin marks and mRNA expression in human pancreatic cell populations
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· Investigators: Chris Stoeckert, Klaus Kaestner, Markus Grompe

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CBP
BETA3 - Isolation and expansion of hESC-derived pancreatic cell populations
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· Investigators: Mark Magnuson, Chris Wright, Gordon Keller, Peter Zandstra

Lay Abstract:

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CBP
FATE - Functional Analysis of TM4SF4 during Embryogenesis
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· Investigators: Lori Sussel, Didier Stainier, Kristin Artinger

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CBP
SASsy3 - Signal Activated Sentinels for beta-cell development and regeneration
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· Investigators: Mark Magnuson, Palle Serup, Ray MacDonald, Kenneth Zaret, Anne Grapin-Botton

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CBP
preBETA ID - Reagents for beta cell precursor identification
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· Investigators: Philip Streeter, Gordon Keller

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2007-2008 Collaborative Bridging Projects

CBP
SASsy - Signal Activated Sentinels for beta-cell development and regeneration
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· Investigators: Palle Serup, Ray MacDonald, Kenneth Zaret, Anne Grapin-Botton

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CBP
DDMESC - Development of methods and reagents for directed differentiation of mouse embryonic stem cells toward pancreatic beta cells through chemical screening
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· Investigator: Doug Melton

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CBP
BRAVE - Beta cell Regeneration And Vascular Endothelium
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· Investigators: Harry Heimberg, Yuval Dor, Pedro Herrera, Eli Keshet

Lay Abstract:

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CBP
HUMANE - HUmanized Mice for Assays to Normalize Endocrine pancreas function
· View Lay Abstract
· Investigators: Pedro Herrera, Leonard Shultz, Dale Greiner

Lay Abstract:

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CBP
MAD BETA - Monoclonal Antibodies Directed toward the Developing Beta Cell
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· Investigators: Ole Madsen, Gerard Gradwohl, Joshua LaBaer, Kenneth Zaret, Raphael Scharfmann, Philip Streeter, Gordon Keller

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CBP
BETA2 - Pancreatic Beta Cells from Human ES Cells 2
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· Investigators: Mark Magnuson, Gordon Keller, Peter Zandstra

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2006-2007 Collaborative Bridging Projects

CBP
HUMANE - HUmanized Mice for Assays to Normalize Endocrine pancreas function
· View Lay Abstract
· Investigators: Pedro Herrera, Leonard Shultz, Dale Greiner

Lay Abstract:

Not yet available [ Hide ]

CBP
DDMESC - Development of methods and reagents for directed differentiation of mouse embryonic stem cells toward pancreatic beta cells through chemical screening
· View Lay Abstract
· Investigator: Doug Melton

Lay Abstract:

Not yet available [ Hide ]

CBP
BETA - Pancreatic Beta Cells from Human ES Cells
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· Investigators: Mark Magnuson, Chris Wright, Gordon Keller

Lay Abstract:

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CBP
MAD BETA - Monoclonal Antibodies Directed toward the Developing Beta Cell
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· Investigators: Jan Jensen, Ole Madsen, Gerard Gradwohl, Joshua LaBaer, Philip Streeter, Gordon Keller

Lay Abstract:

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CBP
SASsy - Signal Activated Sentinels for beta-cell development and regeneration
· View Lay Abstract
· Investigators: Palle Serup, Ray MacDonald, Kenneth Zaret, Anne Grapin-Botton

Lay Abstract:

Not yet available [ Hide ]

CBP
BRAVE - Beta cell Regeneration And Vascular Endothelium
· View Lay Abstract
· Investigators: Harry Heimberg, Yuval Dor, Pedro Herrera, Eli Keshet

Lay Abstract:

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CBP
MATURE - Transcriptional networks of the mature beta cell
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· Investigators: Roland Stein, Lori Sussel, Klaus Kaestner, Chris Newgard

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CBP
NEAT - NEtwork Analysis of Transcription in the developing pancreas
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· Investigators: Lori Sussel, Klaus Kaestner, Maike Sander, Shridhar Hannenhalli

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