David Gifford, Ph.D - Co-investigator Profile
We have developed engineered mouse stem cell lines and computational models of pancreatic development to gain insight into potential therapeutics for diabetes. Our stem cell work is identifying in vitro differentiation protocols to create pancreatic progenitors, and we are experimentally elucidating the molecular events that occur during the development of these progenitors using a variety of high-throughput technologies (RNA Seq, ChIP Seq, Mass Spectrometry). Data from these experiments are processed with computational methods developed by our laboratory to reveal biological mechanisms for further exploration.
computational biology, computational genomics, genomics,