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Bing Ren, Ph.D.

Professor
University of California San Diego
Cellular and Molecular Medicine

9500 Gilman
La Jolla, CA 92093-0653
United States

p. (858) 822-5766
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Bing Ren, Ph.D. - Co-investigator Profile

Dr. Ren is currently Member of the Ludwig Institute for Cancer Research (LICR) and Professor of Cellular and Molecular Medicine at the University of California, San Diego School of Medicine. He leads the San Diego Epigenome Center, one of four NIH-sponsored Reference Epigenome Mapping Centers as part of the Roadmap Epigenomics project.  He obtained his Ph.D. from Harvard University in 1998, where he studied mechanisms of transcriptional repression under the guidance of Dr. Tom Maniatis. From 1998 to 2001, he continued to research mechanisms of gene regulation and genomics as a postdoctoral fellow in Dr. Richard Young’s laboratory at Whitehead Institute.  During this period he developed the ChIP-chip analysis method.  At UCSD and LICR, Dr. Ren continued to use genomic approaches investigate the gene regulatory networks and epigenetic mechanisms in eukaryotic cells. Research accomplishments from the laboratory include development of high throughput method for mapping transcription factor binding sites in the human genome, comprehensive mapping of promoters, enhancers, and insulator elements in the human genome, and characterization of the epigenomic landscapes in pluripotent and lineage-committed human cells.

Scientific Interests/Keywords

Epigenetics, Epigenome, ENCODE, gene regulation, embryonic stem cells

Professor, Ren Lab

Click to view the profile for Feng Yue, Ph.D..
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Publication Citation
21131980 Egelhofer TA, Minoda A, Klugman S, Lee K, Kolasinska-Zwierz P, Alekseyenko AA, Cheung MS, Day DS, Gadel S, Gorchakov AA, Gu T, Kharchenko PV, Kuan S, Latorre I, Linder-Basso D, Luu Y, Ngo Q, Perry M, Rechtsteiner A, Riddle NC, Schwartz YB, Shanower GA, Vielle A, Ahringer J, Elgin SC, Kuroda MI, Pirrotta V, Ren B, Strome S, Park PJ, Karpen GH, Hawkins RD, Lieb JD An assessment of histone-modification antibody quality. (2011) Nat Struct Mol Biol 18: 91-3 (Added 2012-03-14 18:27:09.442206)
20452322 Hawkins RD, Hon GC, Lee LK, Ngo Q, Lister R, Pelizzola M, Edsall LE, Kuan S, Luu Y, Klugman S, Antosiewicz-Bourget J, Ye Z, Espinoza C, Agarwahl S, Shen L, Ruotti V, Wang W, Stewart R, Thomson JA, Ecker JR, Ren B Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. (2010) Cell Stem Cell 6: 479-91 (Added 2012-03-14 18:25:23.781325)
19918365 Hon G, Wang W, Ren B Discovery and annotation of functional chromatin signatures in the human genome. (2009) PLoS Comput Biol 5: e1000566 (Added 2012-03-14 18:27:34.623069)
19295514 Heintzman ND, Hon GC, Hawkins RD, Kheradpour P, Stark A, Harp LF, Ye Z, Lee LK, Stuart RK, Ching CW, Ching KA, Antosiewicz-Bourget JE, Liu H, Zhang X, Green RD, Lobanenkov VV, Stewart R, Thomson JA, Crawford GE, Kellis M, Ren B Histone modifications at human enhancers reflect global cell-type-specific gene expression. (2009) Nature 459: 108-12 (Added 2012-03-14 18:25:53.394929)
19212405 Visel A, Blow MJ, Li Z, Zhang T, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Wright C, Chen F, Afzal V, Ren B, Rubin EM, Pennacchio LA ChIP-seq accurately predicts tissue-specific activity of enhancers. (2009) Nature 457: 854-8 (Added 2012-03-14 18:26:21.092912)
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