Bing Ren, Ph.D. - Co-investigator Profile
Dr. Ren is currently Member of the Ludwig Institute for Cancer Research (LICR) and Professor of Cellular and Molecular Medicine at the University of California, San Diego School of Medicine. He leads the San Diego Epigenome Center, one of four NIH-sponsored Reference Epigenome Mapping Centers as part of the Roadmap Epigenomics project. He obtained his Ph.D. from Harvard University in 1998, where he studied mechanisms of transcriptional repression under the guidance of Dr. Tom Maniatis. From 1998 to 2001, he continued to research mechanisms of gene regulation and genomics as a postdoctoral fellow in Dr. Richard Young’s laboratory at Whitehead Institute. During this period he developed the ChIP-chip analysis method. At UCSD and LICR, Dr. Ren continued to use genomic approaches investigate the gene regulatory networks and epigenetic mechanisms in eukaryotic cells. Research accomplishments from the laboratory include development of high throughput method for mapping transcription factor binding sites in the human genome, comprehensive mapping of promoters, enhancers, and insulator elements in the human genome, and characterization of the epigenomic landscapes in pluripotent and lineage-committed human cells.
Epigenetics, Epigenome, ENCODE, gene regulation, embryonic stem cells