Hans-Peter Elsaesser, Ph.D.

Professor
Philipps-Universität Marburg
Institute of Cytobiology and Cytopathology

Robert Koch Str. 6
Marburg, 35037
Germany

p. +4964212864075
f. +4964212866414
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Hans-Peter Elsaesser, Ph.D. - Co-investigator Profile

My group is interested in the function of the Myc-binding transcription factor Miz1 in skin, mammary gland and Schwann cells. We are trying to converge this research line with our interest in autophagy. Since about 2 years we are using in collaboration von Armin Zankel from Graz, Austria, the so called serial block-faced scanning electron microscopy for high resolution 3D reconstructions of cells and tissues. Together with Ray MacDonalds group from the UTSMC in Dallas and Christopher Wrights group from the Vanderbilt University in Nashville we use this approach to analyse the 3D structure of the delamination complex in the developing pancreas of the mouse.

Scientific Interests/Keywords

sking agin, regulation of autophagy in higher eukaryotic cells, function of the Myc-binding protein Miz1 in keratinocytes and in cells of the mammary gland

Publication	Citation
22509363	Hönnemann J, Sanz-Moreno A, Wolf E, Eilers M, Elsässer HP Miz1 is a critical repressor of cdkn1a during skin tumorigenesis. (2012) PLoS One 7: e34885 (Added 2013-04-23 09:30:53.191165)
20398665	Masui T, Swift GH, Deering T, Shen C, Coats WS, Long Q, Elsässer HP, Magnuson MA, MacDonald RJ Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells. (2010) Gastroenterology 139: 270-80 (Added 2013-04-23 09:40:34.426046)
17635993	Gebhardt A, Kosan C, Herkert B, Möröy T, Lutz W, Eilers M, Elsässer HP Miz1 is required for hair follicle structure and hair morphogenesis. (2007) J Cell Sci 120: 2586-93 (Added 2013-04-23 09:33:25.981554)
16391002	Gebhardt A, Frye M, Herold S, Benitah SA, Braun K, Samans B, Watt FM, Elsässer HP, Eilers M Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1. (2006) J Cell Biol 172: 139-49 (Added 2013-04-23 09:34:49.529036)
16126192	Hale MA, Kagami H, Shi L, Holland AM, Elsässer HP, Hammer RE, MacDonald RJ The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas. (2005) Dev Biol 286: 225-37 (Added 2013-04-23 09:38:33.633105)
14747941	Gebhardt A, Ackermann W, Unver N, Elsässer HP Expression of galectin-3 in the rat pancreas during regeneration following hormone-induced pancreatitis. (2004) Cell Tissue Res 315: 321-9 (Added 2013-04-23 09:37:28.122217)
14560010	Adhikary S, Peukert K, Karsunky H, Beuger V, Lutz W, Elsässer HP, Möröy T, Eilers M Miz1 is required for early embryonic development during gastrulation. (2003) Mol Cell Biol 23: 7648-57 (Added 2013-04-23 09:35:57.798763)

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