Karen Schachter, Ph.D
Post-doctoral Fellow
Copenhagen University
The Danish Stem Cell Center
The Danish Stem Cell Center, Panum Institute 6.4.24, Copenhagen University, Blegdamsvej 3B
Copenhagen N,
2200
Denmark
p. +4529632860
· email
Karen Schachter, Ph.D - Affiliate Profile
I am interested in understanding how human embryonic stem cells can be efficently differentiated into insulin-producing beta cells. In particular, I want to understand how the cells integrate cues from the environment to initiate differentiation into definitive endoderm.
Scientific Interests/Keywords
Definitive endoderm, Primitive Streak, Nodal signaling, Wnt signaling, human embryonic stem cells, defined culture conditions
Affiliate of
Publications
| Publication | Citation |
|---|---|
| 22275192 | Hong M, Schachter KA, Jiang G, Krauss RS Neogenin regulates Sonic Hedgehog pathway activity during digit patterning. (2012) Dev Dyn 241: 627-37 (Added 2013-03-12 10:00:53.095095) |
| 21802063 | Bae GU, Domené S, Roessler E, Schachter K, Kang JS, Muenke M, Krauss RS Mutations in CDON, encoding a hedgehog receptor, result in holoprosencephaly and defective interactions with other hedgehog receptors. (2011) Am J Hum Genet 89: 231-40 (Added 2013-03-12 10:01:02.548389) |
| 19186244 | Schachter KA, Krauss RS Murine models of holoprosencephaly. (2008) Curr Top Dev Biol 84: 139-70 (Added 2013-03-12 10:01:09.014124) |
| 16687404 | Schachter KA, Du Y, Lin A, Gallo KA Dynamic positive feedback phosphorylation of mixed lineage kinase 3 by JNK reversibly regulates its distribution to Triton-soluble domains. (2006) J Biol Chem 281: 19134-44 (Added 2013-03-12 10:01:16.083032) |
| 16253996 | Du Y, Böck BC, Schachter KA, Chao M, Gallo KA Cdc42 induces activation loop phosphorylation and membrane targeting of mixed lineage kinase 3. (2005) J Biol Chem 280: 42984-93 (Added 2013-03-12 10:01:19.007185) |
| 15174310 | Chávez R, Schachter K, Navarro C, Peirano A, Bull P, Eyzaguirre J The acetyl xylan esterase II gene from Penicillium purpurogenum is differentially expressed in several carbon sources, and tightly regulated by pH. (2004) Biol Res 37: 107-13 (Added 2013-03-12 10:01:27.321699) |
| 12137954 | Chávez R, Schachter K, Navarro C, Peirano A, Aguirre C, Bull P, Eyzaguirre J Differences in expression of two endoxylanase genes (xynA and xynB) from Penicillium purpurogenum. (2002) Gene 293: 161-8 (Added 2013-03-12 10:01:30.573315) |
| 11715859 | Chávez R, Almarza C, Schachter K, Peirano A, Bull P, Eyzaguirre J Structure analysis of the endoxylanase A gene from penicillium purpurogenum. (2001) Biol Res 34: 217-26 (Added 2013-03-12 10:01:33.414741) |
