Kristin Artinger, Ph.D. - Investigator Profile
Research in my lab is directed toward an understanding of the molecular, genetic and developmental mechanisms involved in the patterning of the early neural crest during vertebrate embryogenesis. There are several different populations of cells at the lateral border of the neural plate in addition to neural crest cells including Rohon-Beard sensory neurons and placodal cells. One of these cell populations, namely neural crest cells, have the extraordinary ability to retain stem cell-like characteristics during development and give rise to multiple derivatives, including peripheral neurons, pigment cells and craniofacial cartilage, which makes up most of the vertebrate face. This combination has made it an attractive model system to study cell fate determination.
zebrafish, embryogenesis, patterning, neural development
|19777590||Birkholz DA, Olesnicky Killian EC, George KM, Artinger KB Prdm1a is necessary for posterior pharyngeal arch development in zebrafish. (2009) Dev Dyn 238: 2575-87 (Added 2010-01-09 12:18:13.670044)|
|19576198||Olesnicky Killian EC, Birkholz DA, Artinger KB A role for chemokine signaling in neural crest cell migration and craniofacial development. (2009) Dev Biol 333: 161-72 (Added 2010-01-09 12:18:36.731072)|
|18191829||Rossi CC, Hernandez-Lagunas L, Zhang C, Choi IF, Kwok L, Klymkowsky M, Artinger KB Rohon-Beard sensory neurons are induced by BMP4 expressing non-neural ectoderm in Xenopus laevis. (2008) Dev Biol 314: 351-61 (Added 2008-10-21 16:05:08)|
|15581883||Kaji T, Artinger KB dlx3b and dlx4b function in the development of Rohon-Beard sensory neurons and trigeminal placode in the zebrafish neurula. (2004) Dev Biol 276: 523-40 (Added 2008-10-21 16:05:22)|
|12466200||Woda JM, Pastagia J, Mercola M, Artinger KB Dlx proteins position the neural plate border and determine adjacent cell fates. (2003) Development 130: 331-42 (Added 2008-10-21 16:05:32)|