Research Investigators

Photo Principal Investigator (sort up \| down) Institution (sort up \| down)	Research Interests
Kristin Artinger, Ph.D. UCHSC	zebrafish, embryogenesis, patterning,
Anil Bhushan, Ph.D. University of California, Los Angeles	beta cell regeneration, cell cycle regulation, embryogenesis
Ondine Cleaver, Ph.D. UT Southwestern Medical Center	Developmental biology, organogenesis, angiogenesis/vasculogenesis, stem cell differentiation
Yuval Dor Hebrew University-Hadassah Medical School	Tissue dynamics, Organ size control, Stem cells, Pancreas development, Beta cell regeneration
Marvin Gershengorn NIDDK/NIH	Stem Cells
Richard Goodman Oregon Health & Science University	Intracellular signals
Gerard Gradwohl Institute of Genetics and Molecular and Cellular Biology (IGBMC)	Genetic control of pancreatic and intestinal endocrine cells differentiation
Anne Grapin-Botton EPFL	Mechanisms of organ formation in the endoderm. Endocrine cell development.
Dale Greiner University of Massachusetts Medical School
Markus Grompe Oregon Health Sciences University	metabolic liver diseases, molecular genetics of Fanconi Anemia, hepatic and pancreatic stem cells
Guoqiang Gu, Ph.D. Vanderbilt University	islet, cell lineage, cell marking, stem cell, regeneration, maturation, maintenance.
David Harlan NIDDK/NIH	Pathogenesis of type 1 diabetes mellitus, Rejection organs/tissues transplanted with diabetes
Harry Heimberg Vrije Universiteit Brussels	The biology of the pancreatic (pre)beta-cell. Recombinant adeno- and lentivirus construction to analyze differential gene expression.
Pedro Herrera, Ph.D. University of Geneva Medical School	pancreas development; beta cell development and generation
Klaus Kaestner, Ph.D. University of Pennsylvania	Transcriptional Regulation of Pancreas, Liver and Gut Development in Mammals, Microarray, Transgenic Models
Gordon Keller Ontario Cancer Institute/McEwen Centre for Regenerative Medicine	embryonic hematopoietic and vascular systems
Eugene Kolker, Ph.D. Head, Bioinformatics & High-Throughput Data Analysis Laboratory
Teresa Ku, Ph.D. Beckman Research Institute of the City of Hope	Committing ES Cells to Pancreatic Cells; Purification and In Vitro Expansion of Pancreatic Beta-cell Progenitors.
Ray MacDonald University of Texas Southwestern	pancreatic gene transcription, transcriptional control of organogenesis, pancreatic development
Ole Madsen Hagedorn Research Institute	Our main focus with the BCBC is to generate novel antibody tools for important factors/markers for the different stages of pancreatic maturation. Such reagents will be made available through the Antibody Core.
Mark Magnuson, M.D. Vanderbilt University	Pancreas Development, Mouse Models, Genetic Engineering of Mouse ES Cells, Insulin Secretion
Melissa Mahoney, Ph.D. University of Colorado
Ahmed Mansouri Max-Planck Institute	mouse ES cells, endocrine pancreas, Parkinson disease, Midbrain development, in vitro differentiation of ES cells
Doug Melton, Ph.D. Harvard / HHMI	Microarray, Mouse/Human Stem Cell, Embryonic Development, Islet Cells, Pancreas Development
Charles Murtaugh, Ph.D. University of Utah	Notch, Wnt, lineage-tracing, metaplasia, mouse
Alvin Powers, M.D. Vanderbilt University	diabetes, islet function, islet transplantation, vascularization
Maike Sander, Ph.D. University of California at San Diego	Genetic control of pancreatic cell differentiation, using mouse as a model system.
Raphael Scharfmann INSERM	Diabetes
Henrik Semb Lund University	pancreas development, human embryonic stem cells, beta cell differentiation, morphogenesis, epithelial-mesenchymal interactions, cell adhesion, cell migration, blood vessels
Palle Serup Hagedorn Research Institute	Pancreatic development. Promoter and transcription factor analyses.
Leonard Shultz The Jackson Laboratory
Didier Stainier University of California, San Francisco	The Stainier lab is taking a genetic approach in zebrafish to study vertebrate endoderm, heart and blood vessel formation and function. We are working with several mutations that affect distinct aspects of endodermal and/or cardiovascular development.
Ben Stanger, M.D. University of Pennsylvania	Organogenesis, Development, Notch, Size Regulation, Morphogenesis
Roland Stein, Ph.D. Vanderbilt University	Control of insulin gene transcription and islet development
Chris Stoeckert University of Pennsylvania	Bioinformatics
Philip Streeter, Ph.D. Oregon Health & Science University
Lori Sussel, Ph.D. Columbia University	Genetic Differentiation of Endocrine Pancreatic Cells
Chris Wright Vanderbilt University	Molecular embryology/vertebrate embryogenesis/transcription factors/intercellular signaling
Peter Zandstra University of Toronto
Kenneth Zaret Fox Chase Cancer Center	specification of liver cells