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The BCBC website will be unavailable from July 30th at 9 AM CST to August 1st at 9AM CST.

The BCBC Coordinating Center informatics group is performing a scheduled maintenance update of the BCBC website. Deployed will be various updates and improvements necessary for the third funding cycle of the BCBC, which starts on August 1, 2010. We apologize for any inconvenience.

If you need immediate assistance, please refer to the contacts below:


Participants of the BCBC 3.0

Architecture and Communication Controlling the Efficient Generation of Beta Cells

Chris Wright (PI), Vanderbilt University Medical Center, Nashville, TN
Anne Grapin-Botton, ISREC-EPFL, Lausanne, Switzerland
Ray MacDonald, University of Texas Southwestern, Dallas, TX
Henrik Semb, Lund University, Lund, Sweden
Mark Magnuson, Vanderbilt University Medical Center, Nashville, TN

Formation of Endocrine Pancreas Progenitors

Doris Stoffers (PI), University of Pennsylvania, Philadelphia, PA
Maureen Gannon, Vanderbilt University Medical Center, Nashville, TN
Klaus Kaestner, University of Pennsylvania, Philadelphia, PA

Genetic Control of Pancreatic Endocrine Cell Development

Mark Magnuson (PI), Vanderbilt University Medical Center, Nashville, TN
Guoqiang Gu, Vanderbilt University Medical Center, Nashville, TN
Ray MacDonald, University of Texas Southwestern, Dallas, TX
Chris Stoeckert, University of Pennsylvania, Philadelphia, PA
Lori Sussel, Columbia University, New York, NY

Beta Cell Regeneration by Reprogramming of Adult Pancreatic Cells

Pedro Herrera (PI), University of Geneva, Medical School, Geneva, Switzerland

Molecular Mechanisms of Human Murine Beta Cell Proliferation and Regeneration

Alvin Powers (PI), Vanderbilt University Medical Center, Nashville, TN
Dale Greiner, University of Massachusetts, Medical School, Boston, MA
David Harlan, University of Massachusetts, Medical School, Boston, MA
Pedro Herrera, University of Geneva, Medical School, Geneva, Switzerland
Leonard Shultz, The Jackson Laboratory, Bar Harbor, ME
Roland Stein, Vanderbilt University Medical School, Nashville, TN
Seung Kim, Stanford University, Palo Alto, CA

Epigenetic and Genetic Control of Human and Murine Beta Cell Development and Fate

Seung Kim (PI) Stanford University, Palo Alto, CA
Anil Bhushan, University of California, Los Angeles, CA
Howard Chang, Stanford University, Palo Alto, CA
Michael Snyder, Stanford University, Palo Alto, CA

Expanding Beta-Cell Mass

Michael German (PI), University of California, San Francisco, CA
Didier Stainier, University of California, San Francisco, CA
Matthias Hebrok, University of California, San Francisco, CA
Feroz Papa, University of California, San Francisco, CA

Multi-Disciplinary Approaches to Driving Therapeutic Human Beta Cell Replication

Andrew Stewart (PI), University of Pittsburgh, Pittsburgh, PA
Chris Newgard, Duke University, Durham, NC

Novel Sources of Transplantable Beta-Cell Replacements

Markus Grompe (PI), Oregon Health & Science University, Portland, OR
Klaus Kaestner, University of Pennsylvania, Philadelphia, PA
Mark Kay, Stanford University, Palo Alto, CA
Philip Streeter, Oregon Health & Science University, Portland, OR

Epigenetic Strategies for the In-Vitro Generation of Replacement Beta Cells

Maike Sander (PI), University of California, San Diego, CA
Jorge Ferrer, Endocrinology, Hospital Clinic de Barcelona, Barcelona, Spain
Klaus Kaestner, University of Pennsylvania, Philadelphia, PA
Karl Willert, University of California, San Diego, CA

Regenerating Beta Cells by Lineage Reprogramming

Douglas Melton (PI), Harvard University, Boston, MA
Qaio Zhou, Harvard University, Boston, MA

Generation of Functional Beta Cells from Stem and Progenitor Cells

Gordon Keller (PI), McEwen Centre for Regenerative Medicine/University Health Network, Toronto, Canada
Peter Zandstra, University of Toronto, Toronto, Canada
Philip Streeter, Oregon Health & Science University, Portland, OR
Mervin Yoder, Indiana University, Indianapolis, IN
Leonard Shultz, The Jackson Laboratory, Bar Harbor, ME

Epigenetic and Chemical Approaches to Generate Function Beta Cells

Yi Zhang (PI), University of North Carolina at Chapel Hill/Howard Hughes Medical Institute, Chapel Hill, NC

Epigenetic Regulation and Enhancement of Beta Cell Differentiation

Arthur Riggs (PI), City of Hope, Los Angeles, CA

Epigenomics of the Regenerating and Aging Beta-Cell

Klaus Kaestner (PI), University of Pennsylvania, Philadelphia, PA
Doris Stoffers, University of Pennsylvania, Philadelphia, PA

Signaling and Epigenetic Control of Beta Cell Development and Regeneration

Ken Zaret (PI), University of Pennsylvania, Philadelphia, PA
Gerard Gradwohl, Institute of Genetics and Molecular and Cellular Biology (IGMCB), Strasbourg, France
Harry Heimberg, University of Brussels, Brussels, Belgium
Eugene Kolker, Seattle Children's Research Institute, Seattle, WA
Raphael Scharfmann, INSERM, Paris, France

Coordinating Center for the Beta Cell Biology Consortium

Mark Magnuson (PI), Vanderbilt University Medical Center, Nashville, TN
Ole Madsen, Hagedorn Research Institute, Gentofte, Denmark
Chris Stoeckert, University of Pennsylvania, Philadelphia, PA