Welcome to the BCBC
The mission of the Beta Cell Biology Consortium (BCBC) is to facilitate interdisciplinary collaborations to advance our understanding of pancreatic islet development and function, with the goal of developing innovative therapies to correct the loss of beta cell mass in diabetes, including cell reprogramming, regeneration and replacement. (read more)
Genes and Studies
Enter a keyword to find genes or studies available via Beta Cell Genomics:
(Eg. Pdx1)
Submit a Resource
To start adding a new resource, simply click on the above button.
Tutorials
Latest Reagents & Resources
Most Recent from All Collections
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Sander monolayer CyT49 differentiation protocol
Released on Jan. 17, 2012, to the BCBC. -
Melton hESC differentiation protocol
Released on Jan. 17, 2012, to the BCBC. -
FGF2 Semb hESC differentiation protocol
Released on Jan. 17, 2012, to the BCBC. -
Pancreatic differentiation of hESCs Keller
Released on Jan. 17, 2012, to the BCBC. -
Pancreas Dissociation for Virus-Mediated Gene Transfer
Released on Jan. 13, 2012, to the BCBC.
Antibodies
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Monoclonal Mouse Pax4 raised in Mouse
Released on Sep. 29, 2011, to the BCBC. -
Monoclonal Mouse Pax4 raised in Mouse
Released on Sep. 29, 2011, to the BCBC. -
Monoclonal Mouse Pax4 raised in Mouse
Released on Sep. 29, 2011, to the BCBC. -
Polyclonal Human Ngn3 raised in Sheep
Released on Sep. 29, 2011, to the public. -
Monoclonal Mouse TMEM27 raised in Mouse
Released on Sep. 29, 2011, to the public.
Adenoviruses
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OE.Human.CDK6.Tetracycline Responsive Element (TRE)
Released on Jun. 2, 2011, to the public. -
OE.Human.PDX1.CMV
Released on Jun. 2, 2011, to the BCBC. -
OE.Human.NKX6-1.CMV
Released on Jun. 2, 2011, to the BCBC. -
OE.E. coli.rtTA.CMV
Released on Jun. 2, 2011, to the public. -
OE.Mouse.Arx.CMV
Released on Apr. 21, 2011, to the BCBC.
Functional Genomics Studies
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Transcriptional profiling of Insm1-dependent pancreatic endocrine differentiation
Released on Dec. 13, 2011, to the BCBC. -
Transcriptional and epigenetic profiling of the progression of hESCs to beta cells
Released on Dec. 13, 2011, to the BCBC. -
Whole transcriptome analysis of Sox17.Epi and Endo cells in mouse embryos
Released on Dec. 13, 2011, to the BCBC. -
Pancreatic beta cell identity is maintained by DNA methylation-mediated repression of Arx
Released on Jul. 29, 2011, to the public. -
Exendin-4 treatment of Pancreatic Islets
Released on Jul. 29, 2011, to the public.
Mouse ES Cell Lines
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Pdx1rTTA
Released on Dec. 22, 2011, to the BCBC. -
Pdx1Cre
Released on Dec. 22, 2011, to the BCBC. -
Ins2Apple.LCA
Released on Dec. 22, 2011, to the BCBC. -
NepnCherry
Released on Dec. 22, 2011, to the BCBC. -
Rosa26228.TOP.CFP
Released on Dec. 22, 2011, to the BCBC.
Mouse Strains
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Nkx2.2(Cre.EGFP)Suss
Released on Jan. 4, 2012, to the BCBC. -
Rosa26(228.AR8.TA.mCherry)Hri
Released on Jan. 4, 2012, to the BCBC. -
Ngn3(HA.LCA)Ggu
Released on Dec. 22, 2011, to the BCBC. -
Rosa26(Setd5.GFP)Mgn
Released on Dec. 22, 2011, to the BCBC. -
Rosa26(TetO.NRSF)Msan
Released on Dec. 22, 2011, to the BCBC.
Protocols
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Sander monolayer CyT49 differentiation protocol
Released on Jan. 17, 2012, to the BCBC. -
Melton hESC differentiation protocol
Released on Jan. 17, 2012, to the BCBC. -
FGF2 Semb hESC differentiation protocol
Released on Jan. 17, 2012, to the BCBC. -
Pancreatic differentiation of hESCs Keller
Released on Jan. 17, 2012, to the BCBC. -
Pancreas Dissociation for Virus-Mediated Gene Transfer
Released on Jan. 13, 2012, to the BCBC.
Miscellaneous Resources
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Metagene model for the mouse genome assembly (mm9)
Released on Dec. 15, 2011, to the public. -
Key Tools for ChIP-seq Data Analysis and Comparison
Released on May. 4, 2011, to the BCBC. -
Analyzing RNA-Seq data as aligned reads, expression profiles, and networks
Released on May. 4, 2011, to the BCBC. -
RNA-seq and ChIP-seq data management
Released on May. 4, 2011, to the BCBC. -
Key Tools for ChIP-seq Data Analysis and Comparison
Released on May. 3, 2011, to the BCBC.
News & Events
- Mar 25, 2012 - Keystone Symposia “Advances in Islet Biology”
- Jan 02, 2012 - New Human ES Cell Lines Approved for NIH-Funded Research
- Dec 02, 2011 - JDRF Funding Opportunity - EOI in Encapsulation Technology
Articles
- Jan. 27, 2012 - Specific control of pancreatic endocrine beta cell and delta cell mass by Class IIa Histone Deacetylases HDAC4, HDAC5, and HDAC9 New
- Nov. 30, 2011 - Context-specific alpha-to-beta cell reprogramming by forced Pdx1 expression
- Nov. 21, 2011 - Bace2 is a beta cell-enriched protease that regulates pancreatic beta cell function and mass
Career Opportunities
- Jan. 6, 2012 Principal Investigator in Stem Cell Biology and Diabetes - Keller group
If you would like to post a position, please read the instructions.




